Jack Byrne and Derrick Williams have been named by manager Stephen Kenny in a squad of 25 for the matches against Slovakia, Wales and Finland.
It's the first time Shamrock Rovers midfielder Byrne and Blackburn Rovers defender Williams have been named in one of Kenny's squads.
The Euro 2020 playoff semi-final between the Republic of Ireland and Slovakia takes place in Bratislava on Thursday 8th October.
Robbie Brady and Callum O'Dowda have both been included, despite injury concerns over the pair.
O'Dowda returned to training on Saturday, while Brady is nursing a rib injury.
There is no place in the squad for Troy Parrott, who has an ankle injury.
Sean Maguire, Michael Obafemi and Dara O'Shea are also omitted.
The squad will assemble in Dublin on Sunday before travelling to Slovakia on Tuesday.
Here is the squad in full:
Goalkeepers
Darren Randolph (West Ham United), Caoimhin Kelleher (Liverpool), Mark Travers (Bournemouth).
Defenders
Seamus Coleman (Everton), Matt Doherty (Tottenham Hotspur), Enda Stevens (Sheffield United), Darragh Lenihan (Blackburn Rovers), Shane Duffy (Celtic, on loan from Brighton & Hove Albion), John Egan (Sheffield United), Derrick Williams (Blackburn Rovers).
Midfielders
Conor Hourihane (Aston Villa), James McCarthy (Crystal Palace), Harry Arter (Nottingham Forest), Jeff Hendrick (Newcastle United), Alan Browne (Preston North End), Jayson Molumby (Brighton & Hove Albion), Jack Byrne (Shamrock Rovers), Robbie Brady (Burnley).
Forwards
Callum Robinson (West Bromwich Albion), Callum O’Dowda (Bristol City), James McClean (Stoke City), Aaron Connolly (Brighton & Hove Albion), David McGoldrick (Sheffield United), Adam Idah (Norwich City), Shane Long (Southampton).
