Italy's top appeals court has overturned the convictions of Amanda Knox and Raffaele Sollecito for the murder of UK student Meredith Kercher.
The decision is the final ruling in the long-running case.
The pair were found guilty in 2009, then freed in 2011 after the convictions were overturned.
Their convictions were reinstated by another court last year.
Ms Kercher was found dead in 2007 in a flat she shared with Ms Knox.
The couple had always maintained their innocence and the decision by the Court of Cassation puts an end to their long legal battle.
Arline Kercher, the mother of Meredith Kercher, said tonight she was "surprised and very shocked" by the decision of the court.
Meanwhile Amanda Knox issued a statement afterwards: "I am tremendously relieved and grateful for the decision of the Supreme Court of Italy. The knowledge of my innocence has given me strength in the darkest times of this ordeal. And throughout this ordeal, I have received invaluable support from family, friends, and strangers. To them, I say: Thank you from the bottom of my heart. Your kindness has sustained me. I only wish that I could thank each and every one of you in person."
