Former Fine Gael MEP Jim Higgins has failed to retain his seat in Europe.
He was eliminated following the results of the fourth count in the Midlands Northwest constituency.
So far, Luke Ming Flanagan is the only MEP to be elected in Castlebar.
Sinn Fein's Matt Carthy and Fine Gael's Mairead McGuinness are both expected to claim two of the remaining three seats.
But there is a battle for the final spot between two former North West MEP's Independent Marian Harkin and Fianna Fail's Pat the Cope Gallagher.
His party colleague, Thomas Byrne says it is highly unlikely he will out-poll Pat the Cope Gallager.