Up to 500 jobs will be created at Pfizer as the company is investing €1.2 billion in its Dublin facility.
It will bring the company's total workforce in Ireland to around 5,500.
The investment, which is Pfizer’s biggest expansion investment to date in Ireland, will see a new facility built on the site at Grange Castle and will double the capacity for manufacturing at the facility.
The investment and the roles being created will significantly expand manufacturing and laboratory capacity and add new technologies.
The project is currently in the preliminary design phase with construction expected to commence on site in 2024 and the new facility due for completion in 2027.
Mike McDermott, Chief Global Supply Officer with Pfizer, said Grange Castle has played a critical role in the company's global Covid-19 vaccine network, and the investment will help to further expand the site’s broad and robust capabilities.
Pfizer was one of the first pharmaceutical companies to locate in Ireland in 1969.
It has plants across five locations based in Cork, Dublin, and Kildare.