A search for survivors is continuing in northern Afghanistan and Pakistan - after a 7.5 magnitude earthquake.
More than 300 people have been killed and around a thousand injured.
Freezing conditions, heavy rain and snow have been pounding the remote, mountainous areas and communication is poor.
UNICEF is warning that health, nutrition and hygiene services have been badly hit.
I've been speaking to Fundraising Director Ruth Craig
I began by asking her what UNICEF is doing on the ground: