Leo Varadkar has been named as the new Minister for Health in the Cabinet reshuffle.
He will replace James Reilly - who is remaining in Government - taking on the role of Minister for Children.
Meanwhile the Labour Party has failed in its bid to secure the Jobs Ministry - while Pat Rabbitte has lost his place in Cabinet.
The Taoiseach unveiled his new look Cabinet just before 2 o clock today
Enda Kenny removed Jimmy Deenihan and the departure of Phil Hogan has allowed him to make two promotions.
Charlie Flanagan is the new Foreign Affairs Minister - with Simon Coveney taking responsibility for Defence as well as Agriculture.
Heather Humphries is newly promoted to Arts and Heritage - with Paschal Donohue moving up to Transport, Tourism and Sport.
Labour's defeated leadership candidate Alex White is the new Communications Minister - with New Deputy Leader Alan Kelly taking up Environment - and Jan O'Sullivan moving on to Education.
Enda Kenny has paid tribute to his outgoing members.
