Large parts of the US government have shut down after senators failed to agree a budget.
Only 50 of the required 60 senators voted in favour of the short-term spending bill - with five Republicans among those who voted against.
Hundreds of thousands of workers will now be forced to take unpaid leave until politicians agree a budget to fund operations.
While many services will continue operating, many federal employees - including members of the military - will not be paid until a deal is reached.
It is the first time since 2013 that the US government has shut down, and comes after recent months have seen politicians rely on short-term funding legislation in lieu of a longer-term bill.
The status of thousands of young undocumented immigrants - known as 'dreamers' - is one of the key sticking points in the talks.
Republicans and Democrats, meanwhile, have blamed each other for the stalemate.
Senate Majority Leader Mitch McConnell said in a statement: “What we just witnessed on the floor was a cynical decision by Senate Democrats to shove aside millions of Americans for the sake of irresponsible political games."
Democratic leader Chuck Schumer - who met the US president yesterday in a last minute bid to reach a deal - blamed Donald Trump for the shutdown:
— Chuck Schumer (@SenSchumer) January 20, 2018
After the Senate vote, White House Press Secretary Sarah Huckabee Sanders hit out at Democrats as 'obstructionist losers':
— Sarah Sanders (@PressSec) January 20, 2018
It comes as President Trump marks the first anniversary of his inauguration - and these people who voted for him say others are to blame for the shutdown:
The Senate is due to reconvene on Saturday afternoon local time as efforts continue to find a resolution.