Robert Lewandowski has been ruled out of Poland's World Cup qualifier against England on Wednesday due to a knee injury.
The Bayern Munich striker was injured in Poland's 3-0 win over Andorra on Sunday, scoring twice before being taken off in the second half.
The 32-year-old striker, who has 42 goals in just 36 games for Bayern Munich in all competitions this season, has now returned to the German side.
A statement from the Polish FA read: "Clinical and imaging studies have shown damage to the collateral ligament of the right knee.
"The short time remaining until the next match of the national team excludes the participation of the national team captain in this match.
"This would carry too much risk of aggravating the injury. This decision is the only right one, bearing in mind the upcoming Euro 2020 tournament.
"Treatment of this type of injury usually lasts from five to 10 days. Therefore, Robert Lewandowski will return to the club, where he will undergo further rehabilitation."
Lewandowski is on course to score more than 40 goals in the Bundesliga this season having scored 35 goals league games.
He is Poland's all-time record goalscorer with 66 goals in 118 international appearances.
Poland drew 3-3 away to Hungary in their first Group I game, before winning at home to Andorra.
Gareth Southgate's side have started their campaign with wins over San Marino and Albania, which extended their unbeaten run in World Cup qualifiers to 23 games.