Almost 40 walk-in COVID-19 vaccination centres are opening throughout the country from today.
Anyone aged 16 or older who hasn't got their first dose yet can attend one of the clinics.
Damien McCallion, the HSE's national lead for the vaccination programme, says the vast majority of the country's vaccination centres are operating as walk-in sites this weekend.
He has urged people to check the times each site is operating on a walk-in basis, as the times vary significantly from site to site.
Full details of the clinics are available on the HSE's website.
Anyone who attends will be offered either the Pfizer or Moderna vaccine.
There's at least one clinic operating in every county this weekend, with the exception of Longford where the walk-in centre operated yesterday instead.