2,026 people aged under 30 resigned from the HSE last year.
According to Freedom of Information Figures, it's an increase of 15 per cent on the previous year.
Beaumont Hospital consultant, Bill Tormey, says burnout is a major problem facing healthcare staff.
"In the last two years there's been a massive increase in stress on the job because of the Covid-19 crisis."
"They're overworked and on top of that there is increasing paper filling."
"There's also greater demand these days for a better work life balance."
Galway GP Martin Daly says many people leave the HSE to work abroad, in places like New Zealand, Australia, the UK and Canada.
"Many of them would express the view they don't feel valued in their own system whereas they feel valued abroad."
"There appears to be a culture within the HSE of a lack of career pathways in which they can advance professionally."
A total of nearly 7,300 people under 65 quit in 2021 - which is up almost 1,000 on 2020.