Munster have named World Cup winners Damian de Allende and RG Snyman in their starting 15 for Saturday night's Guinness PRO14 clash with Leinster at the Aviva Stadium.
The season resumes this weekend after being on hold for almost six months due to the coronavirus pandemic.
It means Munster head coach Johann van Graan is able to pick Springboks pair De Allende and Snyman for the first time.
Shane Daly makes his fifth start at full-back in his 18th appearance for the province with Ireland internationals Andrew Conway and Keith Earls on either flank.
De Allende is partnered in the centres by Chris Farrell with Conor Murray and JJ Hanrahan in the half-backs.
James Cronin, Niall Scannell and Stephen Archer start in the front row with Snyman and Billy Holland in the engine room.
The side is completed by the back row of captain Peter O’Mahony, Tommy O’Donnell and CJ Stander.
Leinster, playing their first game since February 28th, will be captained by Johnny Sexton.
Leinster head coach Leo Cullen has gone with Jordan Larmour, Dave Kearney and James Lowe as the back three.
Robbie Henshaw and Garry Ringrose form the centre pairing, while Sexton will have Luke McGrath alongside him.
In the pack, Cian Healy and Andrew Porter start at loosehead and tighthead with Rónan Kelleher at hooker.
Ryan Baird gets his first start in an inter-provincial game. and will be joined by Scott Fardy in the second row.
The back row sees Caelan Doris starts at blindside flanker for the first time for Leinster, with Josh van der Flier at openside.
Jack Conan plays for the first time this season having recovered from an ankle injury picked up at the 2019 Rugby World Cup.
His last game for Leinster was last season’s Guinness PRO14 Final.
Munster: Shane Daly; Andrew Conway, Chris Farrell, Damian de Allende, Keith Earls; JJ Hanrahan, Conor Murray; James Cronin, Niall Scannell, Stephen Archer; RG Snyman, Billy Holland; Peter O’Mahony (C), Tommy O’Donnell, CJ Stander.
Replacements: Rhys Marshall, Dave Kilcoyne, John Ryan, Jean Kleyn, Chris Cloete, Craig Casey, Rory Scannell, Matt Gallagher.
Leinster: Jordan Larmour, Dave Kearney, Garry Ringrose, Robbie Henshaw, James Lowe, Johnny Sexton (C), Luke McGrath; Cian Healy, Rónan Kelleher, Andrew Porter, Ryan Baird, Scott Fardy, Caelan Doris, Josh van der Flier, Jack Conan.
Replacements: Seán Cronin, Ed Byrne, Michael Bent, Devin Toner, Will Connors, Jamison Gibson-Park, Ross Byrne, Max Deegan.