Brentford manager Thomas Frank has tested positive for Covid-19.
He's one of two people to return positive results in the latest round of testing at the club.
The news comes just days after he was in the dugout for his side's 2-0 loss to José Mourinho's Spurs in the Carabao Cup.
A statement from the club on Friday afternoon said that Frank will isolate at home for ten days under EFL and Government regulations.
The statement also confirmed that Brentford coach Neil MacFarlane will take charge of the team for their FA Cup game against Middlesbrough on Saturday.
The Brentford statement in full read;
"A full round of Covid-19 tests was conducted at the Brentford FC Training Ground yesterday, Thursday 7 January. During this testing, two positive results were returned. Head Coach Thomas Frank was one of those to return a positive test.
"Thomas will now isolate at home for ten days under EFL and Government regulations. Due to medical confidentiality, we will not give any further details of the other positive test.
"In Thomas’ absence Brentford B Head Coach Neil MacFarlane oversaw First Team training today. He will be in the dugout and in charge of the team tomorrow, Saturday, when The Bees face Middlesbrough in the Emirates FA Cup."
Meanwhile, the Football League confirmed on Friday there have been 112 positive coronavirus test results returned from players and staff in the latest round of screening.
The 66 clubs involved in FA Cup or league matches this weekend were all tested.
EFL sides will move into a new schedule from next week, with twice-weekly tests taking place.