Munster pair Jean Kleyn and Mike Haley are set to make their Ireland debuts in Saturday's World Cup warm-up Test with Italy.
Kleyn's been named in the second row for the game at the Aviva, having only become eligible to play for Ireland today. The South African-born lock is a project player who has completed three-years at Munster.
Haley's the other uncapped player in the matchday-23, and he's been named among the replacements.
There's no room for Jonathan Sexton in the squad, with Joey Carbery starting at out-half and Connacht's Jack Carty on the bench.
Partnering Carbery in the half-backs is Leinster's Luke McGrath, who's given the chance to impress at international level having missed the entire Six Nations campaign through injury.
Garry Ringrose forms a centre partnership with Munster's Chris Farrell, with Dave Kearney and Andrew Conway on the wings and Jordan Larmour at full-back.
Tommy O'Donnell hasn't played an Ireland international since the 2016 Six Nations, and he's named in the back-row with Jordi Murphy and captain Rhys Ruddock.
Kleyn will have the experience of Devin Toner alongside him in the second row.
While the front-row is comprised of the trio of Jack McGrath, Rob Herring and Andrew Porter.
Ireland team v Italy:
15. Jordan Larmour (St Mary’s College/Leinster) 13 caps
14. Andrew Conway (Garryowen/Munster) 12 caps caps
13. Garry Ringrose (UCD/Leinster) 20 caps
12. Chris Farrell (Young Munster/Munster) 5 caps
11. Dave Kearney (Lansdowne/Leinster) 17
10. Joey Carbery (Clontarf/Munster) 18 caps
9. Luke McGrath (UCD/Leinster) 10 caps
1. Jack McGrath (St Marys College/Leinster) 54 caps
2. Rob Herring (Ballynahinch/Ulster) 7 caps
3. Andrew Porter (UCD/Leinster) 14 caps
4. Devin Toner (Lansdowne/Leinster) 64 caps
5. Jean Kleyn (Munster) uncapped
6. Rhys Ruddock (St Mary’s College/Leinster) 21 caps Captain
7. Tommy O’Donnell (UL Bohemians/Munster) 12 caps
8. Jordi Murphy (Lansdowne/Ulster) 27 caps
16. Niall Scannell (Dolphin/Munster) 14 caps
17. Cian Healy (Clontarf/Leinster) 88 caps
18. John Ryan (Cork Constitution/Munster) 18 caps
19. Iain Henderson (Queens University/Ulster) 44 caps
20. Tadhg Beirne (Lansdowne/Munster) 5 caps
21. Kieran Marmion (Galwegians/Connacht) 25 caps
22. Jack Carty (Buccaneers/Connacht) 3 caps
23. Mike Haley (Munster) uncapped